Jason Hein

Associate Professor

Jason Hein received his B.Sc. in biochemistry at the University of Manitoba in 2000. In 2005, he completed his Ph.D. in synthetic organic chemistry as an NSERC PGS scholar under Professor Philip G. Hultin at the same institution. He then moved to the Scripps Research Institute as an NSERC postdoctoral fellow supervised by Professors K. Barry Sharpless and Valery V. Fokin. In 2010, he became a senior research associate with Professor Donna G. Blackmond at Scripps. He began his independent career at the University of California, Merced in 2011 where his work focused on employing in situ kinetic reaction analysis as a means to rapidly profile and study complex networks of reactions. In 2015, he moved to the University of British Columbia to continue the development of reaction analytical techniques to further mechanistic organic chemistry.
Research in the Hein lab is aimed at solving a diverse set of lingering problems in modern organic chemistry, with primary focus towards understanding mechanisms of catalyst induction and deactivation as well as developing techniques to resolve racemic mixtures using coupled preferential crystallization.

Curriculum Vitae
Assistant Professor, University of British Columbia (2015 – present)
Assistant Professor, University of California, Merced (2011 – 2015)
Senior Research Associate under Prof. Donna Blackmond, The Scripps Research Institute, La Jolla (2009 – 2011)
NSERC Postdoctoral Fellow under Profs. K. Barry Sharpless and Valery V. Fokin, The Scripps Research Institute, La Jolla (2005 – 2009)
Ph.D. Student under Prof. Philip G. Hultin, University of Manitoba, Winnipeg (2000 – 2005)
B.Sc. Student, University of Manitoba, Winnipeg (1996 – 2000)

Awards and Honors
American Chemical Society Young Investigator’s Award (2015)
University of California, Merced, Graduate & Research Council Award (2012 – 2014)
NSERC Postdoctoral Fellowship (2006 – 2008)
Unversity of Manitoba Dean of Graduate Studies Student Achievement Award (2005)
Action Canada Fellowship for Outstanding Young Leaders (2004 – 2005)
CSC National Conference Poster Presentation Award (2004)
Hugh J. Anderson Anderson Graduate Award for Academic Achievement (2003 – 2004)
ACS-Pan American Advanced Studies Institute on Green Chemistry Fellowship (2003)
NSERC Post Graduate Scolarship – A&B (2000 – 2004)

Our Group
Postdocs and Research Associates

Josh Derasp

I completed an undergraduate degree in chemistry at the University of Prince Edward Island. I then moved to Ottawa and joined the Beauchemin lab for my PhD where I helped develop novel synthetic transformations of nitrogen containing compounds. I joined the Hein group in June 2019 where I now focus on combining my synthetic organic chemistry background with continuous preferential crystallization. In my spare time I enjoy hiking, camping and working out.

Stephanie Forget

I completed my PhD studies in Chemistry at Dalhousie University (Halifax, Nova Scotia). My dissertation focused on (1) the diversification of natural products using chemical and genetic approaches, and (2) delved into the characterization of enzymes involved in bacterial carbohydrate biosynthesis.  My current interests include the discovery of enzymes for biotechnological applications and the development of methods to efficiently guide these efforts. When not in the lab I enjoy strolling the Sea Wall or sweating it out in a yoga or dance studio.

Sebastian Steiner

I completed my MSc degree in Vienna, Austria, in the field of natural product synthesis, and then moved on to do my PhD in Glasgow, Scotland, in synthesis automation. I am interested in designing tools and writing software to enable lab automation, with a special focus on robotic reaction monitoring. In my spare time I train Historical European Martial Arts (sword fighting!), and I enjoy cooking and baking.

Lars Yunker

I completed my Ph.D. at the University of Victoria under the supervision of Scott McIndoe. My research focus was the elucidation of organometallic reaction mechanisms using continuous online monitoring by mass spectrometry. I joined the Hein group in September 2017 as a Postdoctoral Research Fellow and have transitioned to a Research Associate working to integrate automation tools into our workflow. In my spare time I like to mountain bike, scuba dive, and play computer games.

Tara Zepel

I completed my PhD in Art History at the University of California San Diego where I studied data visualization. I am interested in finding unique ways to visualize and analyze large amounts of information using interdisciplinary methodologies. Outside of the lab, you can find me training for triathlon or experimenting with cooking.
Graduate Students

Melodie Christensen

After receiving my master’s degree in Chemistry from American University, I joined Schering Plough Research Institute, where I developed synthetic routes for drug candidates. A few years later, I moved to the Catalysis and Automation group at Merck, where I shifted my focus to the development of high throughput automation and data rich experimentation capabilities to support process development. I joined the Hein lab in January 2019 and am interested in developing custom automation systems as well as implementing machine learning capabilities to accelerate pharmaceutical process development. In my spare time I practice yoga as often as possible, with some mediation sprinkled in. I also really enjoy food, wine, live music, friends, family and quality time with my husband John.

Ryan Chung

I completed my B.S. in Chemistry with Honors at the University of California, Los Angeles (UCLA) in 2015.  My Ph.D. studies have focused on the design, construction, and deployment of modern in situ reaction monitoring tools to solve difficult problems related to modern synthesis. I am motivated to perform in-depth mechanistic and kinetic studies on complex chemical and physical processes under interrogation, with the intention of obtaining high-density time-course data that can help accelerate chemical discovery and optimization.  In my spare time, I enjoy cooking, exercising, and exploring the city.

Jordan Daponte

I completed my Honours B.Sc. at the University of Toronto with a specialization in biological chemistry. My research interests are focused on developing methods and platforms to monitor heterogeneous and biphasic reactions in order to probe their mechanisms. In my spare time, I enjoy hosting tabletop RPG’s, weightlifting, and playing musical instruments.

Maddie Deem

I completed my B.S. in Biology at the University of Portland in 2017, and began my graduate studies at the University of British Columbia in 2018. I'm interested in process chemistry and organic synthesis. I find great satisfaction in the process of optimization and love the combination of empirical knowledge and creativity inherent in synthetic chemistry. In my spare time, I enjoy running and skiing.

Elena Liles

I completed my undergraduate degree nearby at the University of Victoria where began my research career working on the development of novel transition metal catalysts with Prof Lisa Rosenberg. I’m interested in the development of autonomous labs, particularly  with a focus on developing new tools to better understand reactions with complicated mechanism. Out of the lab I’m an aspiring gardener (from my small apartment balcony) and big book lover.

Junliang Liu

I completed my Bachelor’s degree in the field of chemistry as a collaboratively educated student, I spent 2 years in Tianjin University, China; and the other two years in the University of Waterloo, respectively. Then I joined Hein’s lab in 2018 as a MSc student. My interest is organic synthesis and my goal is to become a skillful synthetic chemist who has a map of reactions in their head. In my spare time, I am very interested in politics and sketching.

Tom Malig

I am from Hamilton, Ontario, and completed my undergraduate degree at the University of Guelph. From there, I started the trip West, stopping in Calgary. At UofC I completed my MSc under the supervision of Dr Tom Back, where I studied radical reactions as a means to probe antioxidant ability of antiarrhythmics. I then continued the trip West, stopping in Vancouver where I joined the Hein Lab. I am working on the development of automated reaction profiling technologies for the ultimate goal of mechanistic elucidation of catalytic reactions. When I’m not in the lab, I like golfing, craft beer, and live music.

Yusuke Sato

I was born and raised in Kyoto, one of the most traditional cities, in Japan. I completed my undergraduate studies at University of Shizuoka, during which I greatly enjoyed spending time under the direction of Prof. Kei Manabe where I worked on developing a reaction with novel directing triphenyl phosphine ligands. Now I monitor reactions with an automated HPLC sampler and React IR in the Hein group. Outside of the lab, I enjoy skating, conversation and working out.
Undergraduate Students

Veronica Lai

I am an undergraduate studying chemistry at the University of British Columbia with a passion for technology. My interests lie in creating software for lab automation and exploring ways how artificial intelligence can be leveraged in the lab. I also enjoy cooking and baking, listening to music, and, once in a blue moon, trying to write music.

Kea Legard

I am currently an undergraduate student at UBC Vancouver conducting research in the Hein lab. My research involves orthogonal reaction monitoring of a variety of reactions using HPLC-MS and React IR. I'm originally from the San Francisco Bay Area in California. When I'm not in the lab, I love trying to bake different types of bread and desserts from around the world.

Jessica Li

I am an undergraduate Chemistry student at UBC entering my fourth year. My research involves monitoring crystallization processes with automated sampling and HPLC or ion chromatography. When not in the lab, I enjoy hiking and baking.

Henry Situ

I completed my BSc in Chemistry at UBC. While working for Dr. Hein in my fourth year I was introduced to automation and robotics which inspired me to pursue my BASc in Mechanical Engineering specializing in Mechatronics. I am interested in the integration of hardware and software to achieve precision movements and controls. In my spare time I enjoying making 3D printable trinkets and tools for other members of the Hein Lab.
Staff

Shad Grunert

I completed my BSc in Chemistry at UBC and Management of Technology MBA at SFU Beedie School of Business. I’ve worked across a number of sectors in industry and academia, from wood science to biofuels, to safety management in academia. In my spare time, I enjoy learning as much as possible about materials science, economics, psychology, and history.

Lauren Koch

Born and raised in Berkeley, California, I moved to Vancouver for my BA. I completed my BA, double majoring in Cultural Anthropology and Linguistics. I enjoy learning about the ingenuity of human communication, how we distinguish ourselves as individuals and communities, and the ways in which the two are interconnected. In my free time, I enjoy trying new foods, hiking, and scuba diving (when I’m lucky enough to have both the time and funds).

Paul Mulyk

Since starting my career, I’ve worked in instrument service, bio-energy research and academic settings always gravitating toward instrument application, method development and troubleshooting. I enjoy having a mix of hardware, software and chemistry problems to work on, such as solving analytical challenges, troubleshooting instrumentation, or re-purposing and re-configuring existing equipment. I'm also interested in programmatic instrument control, as well as new machine learning applications.
Alumni
2018
Postdoc (2017-2018)
Shrinwantu Pal
Research Associate (2018)
PhD (2011-2018)
Vanessa Li
UBC Co-op Student (04/2018-08/2018)
Sojung Kim
Undergraduate Research Assistant (06/2018-08/2018)
Yuejun Guo
Work-Learn Summer Fellowship Student (04/2017-04/2018)
Siomon Jacklin
Project student - CHEM 449 (09/2017-04/2018)
Samantha Brown
Work-Learn student (09/2016-04/2018)
2017
MSc (2015-2017)
PhD (2012-2017)
Josh Koenig
Project student - CHEM 449 (09/2016-04/2017)
2016
Postdoc (2014 - 2016)
Henry Situ
Project student - CHEM 445 (09/2015-04/2016)
Esma El-Atman
Project student - CHEM 445 (09/2015-04/2016)
Vanessa Li
Undergraduate Research Assistant (09/2015-04/2016)
2015
MSc (2012-2015)
Samantha Brown
(2014-2015)
Cassandra Crave
(2014-2015)
Samantha Gaerlan
(2014-2015)
Indyana Polley
(2014-2015)
Carl Posadas
(2014-2015)
Alyssa Jones
(2013-2015)