Hai-Yan He
Email: hyhe@chem.ubc.ca
B.Sc. in Applied Chemistry, Tianjin University
Ph.D. in Biochemistry, Shanghai Institute of Organic Chemistry
Research Interests: Biosynthesis, Biocatalysis, and Crystallography
Representative Publications:
He HY, Yuan H, Tang MC, Tang GL (2014) An unusual dehydratase acting on glycerate and a ketoreductase stereoselectively reducing alpha-ketone in polyketide starter unit biosynthesis. Angew Chem Int Ed Engl. 53(42):11315-9.
He HY, Tang MC, Zhang F, Tang GL (2014) Cis-double bond formation by thioesterase and transfer to ketosynthase in FR901464 biosynthesis. J Am Chem Soc. 136(12):4488-91.
He H-Y, Pan H-X, Wu L-F, Zhang B-B, Chai H-B, Liu W, Tang G-L (2012). Quartromicin Biosynthesis: Two Alternative Polyketide Chains Produced by One Polyketide Synthase Assembly Line. Chem. Biol. 19, 1313–1323.