Selected Publications

(Note: If you would like hard and/or soft copies of these works please feel free to contact us using information from the "Contact Us" Link in the menu)

  1. "Migration time correction for dual pressure capillary electrophoresis in semi-targeted metabolomics study", Zi-Ao Huang, Jiahua Tan, Yueyang Li, Siyu Miao, Kymora B. Scotland, Ben H. Chew, Dirk Lange, David D. Y. Chen, Electrophoresis, 43 (15), 1626-1637 (2022).

  2. "Capillary electrophoresis-mass spectrometry analysis of bisphenol A and its analogues in bottled tea beverages with dynamic pH focusing", Noorfatimah Yahaya, Zi-Ao Huang, Binjun Yan, David D. Y. Chen, Food Chemistry, 372, 131220 (2022).

  3. "Characterization of capillary inner surface conditions with streaming potential", Yuri Chenyakin, David D. Y. Chen, Electrophoresis, 42 (20), 2094-2102 (2021).

  4. "Recent applications of graphene and graphene-based materials as sorbents in trace analysis", Wenqiang Jing, Jiaqin Wang, Bianca Kuipers, Wentao Bi, David D. Y. Chen, TRAC Trends in Analytical Chemistry, 137, 116212 (2021).

  5. "Electrospray ionization stability and concentration sensitivity in capillary electrophoresis-mass spectrometry using a flow-through microvial interface", Lingyu Wang, Yueyang Li, Dazhou Chen, David D. Y. Chen, Electrophoresis, 42, 360-368 (2021).

  6. "Quantification of the bisphosphonate alendronate using capillary electrophoresis mass spectrometry with dynamic pH barrage junction focusing", Tingting Zhao, Lingyu Wang, Yueyang Li, Sijia Chen, Rizhi Wang, David D. Y. Chen, Electrophoresis, 42, 350-359 (2021).

  7. "Quantification of imatinib and related compounds using capillary electrophoresis-tandem mass spectrometry with field-amplified sample stacking", Tingting Zhao, Lingyu Wang, David D. Y. Chen, Electrophoresis, 41, 1843-1850 (2020).

  8. "Enantioselective analysis in complex matrices using capillary electrophoresis-mass spectrometry: A case study of the botanical drug Corydalis Rhizoma", Binjun Yan, Zi-Ao Huang, Noorfatimah Yahaya, David D. Y. Chen, Journal of Chromatography B, 122216 (2020).


  9. "Dynamic pH barrage junction focusing of amino acids, peptides, and digested monoclonal antibodies in capillary electrophoresis–mass spectrometry", Lingyu Wang, Jianhui Cheng, Julie E. McNutt, Gregg B. Morin, David D. Y. Chen, Electrophoresis, 41, 1832-1842 (2020).


  10. "Complementary Methods for de Novo Monoclonal Antibody Sequencing to Achieve Complete Sequence Coverage", Jianhui Cheng, Lingyu Wang, Craig M. Rive, Robert A. Holt, Gregg B. Morin, David D. Y. Chen, Journal of Proteome Research, (2020).


  11. "Determination of urinary prostaglandin E2 as a potential biomarker of ureteral stent associated inflammation", Zi-Ao Huang, Kymora B. Scotland, Yueyang Li, Jiahua Tan, Sonia H. Y. Kung, Ben H. Chew, David D. Y. Chen, Dirk Lange, Journal of Chromatography B, 122107 (2020).


  12. "MP46-19 Identification of a potential biomarker for stent-induced ureteral dysfunction", Kymora B. Scotland, Zi-Ao Huang, Lu Wang, David D. Y. Chen, Ben H. Chew, Dirk Lange, Journal of Urology, 203 (Supplement 4), e681-e681 (2020).

  13. "Bottom-up proteomics of envelope proteins extracted from spinach chloroplast via high organic content CE-MS", Jianhui Cheng, Gregg B. Morin, David D. Y. Chen, Electrophoresis, 41, 370-378 (2020).


  14. "Application of multisegment injection on quantification of creatinine and standard addition analysis of urinary 5-hydroxyindoleacetic acid simultaneously with creatinine normalization", Zi-Ao Huang, Kymora B. Scotland, Yueyang Li, Jian-Ping Guo, Patrick L. McGeer, Dirk Lange, David D. Y. Chen, Electrophoresis, 41, 183-193 (2020).


  15. "Sorbent and solvent co-enhanced direct analysis in real time-mass spectrometry for high-throughput determination of trace pollutants in water", Wenqiang Jing, Yanying Zhou, Jiaqin Wang, Yuanfeng Zhu, Youqi Lv, Wentao Bi, David D. Y. Chen, Talanta, 208, 120378 (2020).

  16. "Analysis of four therapeutic monoclonal antibodies by online capillary isoelectric focusing directly coupled to quadrupole time-of-flight mass spectrometry", Lingyu Wang, David D. Y. Chen, Electrophoresis, 40, 2899-2907 (2019).

  17. "Dispersive Magnetic Solid-Phase Extraction Coupled to Direct Analysis in Real Time Mass Spectrometry for High-Throughput Analysis of Trace Environmental Contaminants", Wenqiang Jing, Yanying Zhou, Jiaqin Wang, Miao Ni, Wentao Bi, David D. Y. Chen, Analytical Chemistry, 91, 11240-11246 (2019).

  18. "RawTools: Rapid and Dynamic Interrogation of Orbitrap Data Files for Mass Spectrometer System Management", Kevin A. Kovalchik, Shane Colborne, Sandra Elizabeth Spencer, Poul H. Sorensen, David D. Y. Chen, Gregg B. Morin, Christopher S. Hughes, Journal of Proteome Research, 18, 700-708 (2019).

  19. "High Resolution Capillary Isoelectric Focusing Mass Spectrometry Analysis of Peptides, Proteins, And Monoclonal Antibodies with a Flow-through Microvial Interface", Lingyu Wang, Tao Bo, Zhengxiang Zhang, Guanbo Wang, Wenjun Tong, David D. Y. Chen, Analytical Chemistry, 90, 9495-9503 (2018).


  20. "Capillary electrophoresis-mass spectrometry for targeted and untargeted analysis of the sub-5 kDa urine metabolome of patients with prostate or bladder cancer: A feasibility study", Matthew S. MacLennan, Miranda G. M. Kok, Laiel Soliman, Alan So, Antonio Hurtado-Coll, David D. Y. Chen, Journal of Chromatography B, 1074-1075, 79-85 (2018).

  21. "Pressure-assisted capillary electrophoresis frontal analysis for faster binding constant determination", Cheng Qian, Su Wang, Hengqing Fu, Robin F. B. Turner, Huihui Li, David D. Y. Chen, Electrophoresis, 39, 1786-1793 (2018).

  22. "Optimization of dynamic pH barrage junction focusing for weakly alkaline or zwitterionic analytes in capillary electrophoresis", Lingyu Wang, Wenjun Tong, David D. Y. Chen, Journal of Chromatography B, 1095, 94-102 (2018).

  23. "Parsing and Quantification of Raw Orbitrap Mass Spectrometer Data Using RawQuant", Kevin A. Kovalchik, Sophie Moggridge, David D. Y. Chen, Gregg B. Morin and Christopher S. Hughes, Journal of Proteome Research, 17, 2237-2247 (2018).


  24. "Characterization of Athabasca lean oil sands and mixed surficial materials: Comparison of capillary electrophoresis/low-resolution mass spectrometry and high-resolution mass spectrometry", MacLennan Matthew S., Peru Kerry M., Swyngedouw Chris, Fleming Ian, Chen David D.Y. and Headley John V., Rapid Communications in Mass Spectrometry, 32(9), 695-702 (2018).

  25. "Characterization of dicarboxylic naphthenic acid fraction compounds utilizing amide derivatization: Proof of concept", Kevin A. Kovalchik, Matthew S. MacLennan, Kerry M. Peru, Chukwuemeka Ajaero, Dena W. McMartin, John V. Headley and David D. Y. Chen, Rapid Communications in Mass Spectrometry, 31(24), 2057-2065 (2017). (Cover paper)


  26. "Different in vitro cellular responses to tamoxifen treatment in polydimethylsiloxane-based devices compared to normal cell culture", Lingyu Wang, Linfen Yu, Samantha Grist, Karen C. Cheung and David D. Y. Chen, Journal of Chromatography B, 1068-1069(Supplement C), 105-111 (2017).

  27. "Nonaqueous capillary electrophoresis mass spectrometry method for determining highly hydrophobic peptides", Jianhui Cheng and David D. Y. Chen, Electrophoresis, (2017) 39(9-10), 1216-1221 (2018). (Cover paper)


  28. "Specific Binding Constant and Stoichiometry Determination in Free Solution by Mass Spectrometry and Capillary Electrophoresis Frontal Analysis", Cheng Qian, Hengqing Fu, Kevin A. Kovalchik, Huihui Li and David D. Y. Chen, Analytical Chemistry, 89(17), 9483-9490 (2017).


  29. "Review of recent developments in determining volatile organic compounds in exhaled breath as biomarkers for lung cancer diagnosis", Jiemin Zhou, Zi-Ao Huang, Ujendra Kumar and David D. Y. Chen, Analytica Chimica Acta, 996, 1-9 (2017). (Cover paper)


  30. "Electroosmotic Flow Dispersion of Large Molecules in Electrokinetic Migration", Akram Khodabandehloo and David D. Y. Chen, Analytical Chemistry, 89(15), 7823-7827 (2017).


  31. "Mobility-based correction for accurate determination of binding constants by capillary electrophoresis-frontal analysis", Cheng Qian, Kevin A. Kovalchik, Matthew S. MacLennan, Xiaohua Huang and David D. Y. Chen, Electrophoresis, 38(12), 1572-1581 (2017).

  32. "Improved sensitivity by post-column chemical environment modification of CE-ESI-MS using a flow-through microvial interface", Jessica May Risley and David D. Y. Chen, Electrophoresis, 38(12), 1644-1648 (2017).

  33. "Standard method design considerations for semi-quantification of total naphthenic acids in oil sands process affected water by mass spectrometry: A review", Kevin A. Kovalchik, Matthew S. MacLennan, Kerry M. Peru, John V. Headley and David D. Y. Chen, Frontiers of Chemical Science and Engineering, (2017).


  34. ""Particle sizing methods for the detection of protein aggregates in biopharmaceuticals", Akram Khodabandehloo and David D. Y. Chen, Bioanalysis, 9(3), 313-326 (2017).

  35. "Quantitative Nonaqueous Capillary Electrophoresis–Mass Spectrometry Method for Determining Active Ingredients in Plant Extracts", Jianhui Cheng, Lingyu Wang, Weifen Liu and David D. Y. Chen, Analytical Chemistry, 89(3), 1411-1415 (2017).


  36. "Potential of capillary electrophoresis mass spectrometry for the characterization and monitoring of amine-derivatized naphthenic acids from oil sands process-affected water", Matthew S. MacLennan, Cai Tie, Kevin Kovalchik, Kerry M. Peru, Xinxiang Zhang, John V. Headley and David D. Y. Chen, Journal of Environmental Sciences, 49, 203-212 (2016).


  37. "Separation of Recombinant Therapeutic Proteins Using Capillary Gel Electrophoresis and Capillary Isoelectric Focusing", Caitlyn A. G. De Jong, Jessica Risley, Alexis K. Lee, Shuai Sherry Zhao and David D. Y. Chen, Capillary Electrophoresis of Proteins and Peptides: Methods and Protocols. N. T. Tran and M. Taverna. New York, NY, Springer New York: 137-149(2016).

  38. "Electrospray Ionization Interface Development For Capillary Electrophoresis–Mass Spectrometry", Jessica M. Risley, Caitlyn A. G. De Jong and David D. Y. Chen, Capillary Electrophoresis–Mass Spectrometry (CE-MS), Wiley-VCH Verlag GmbH & Co. KGaA: 7-39 (2016).

  39. "Capture efficiency of dynamic pH junction focusing in capillary electrophoresis", Lingyu Wang, David MacDonald, Xiaohua Huang and David D. Y. Chen, Electrophoresis, 37(9), 1143-1150 (2016).

  40. "Comparison of Sample Introduction Methods for Continuous Chemical Purification in Two-Dimensional Electro-Fluid-Dynamic Devices", Chang Liu and David D. Y. Chen, Analytical Chemistry, 86(22), 11380-11386 (2014).


  41. "Simple Capillary Electrophoresis–Mass Spectrometry Method for Complex Glycan Analysis Using a Flow-Through Microvial Interface", Roxana G. Jayo, Morten Thaysen-Andersen, Petrus W. Lindenburg, Rob Haselberg, Thomas Hankemeier, Rawi Ramautar and David D. Y. Chen, Analytical Chemistry, 86(13), 6479-6486 (2014).


  42. "Capillary electrophoresis mass spectrometry using a flow through microvial interface for cationic metabolome analysis", Petrus W Lindenburg, Rawi Ramautar, Roxana G Jayo, David DY Chen, and Thomas Hankemeier, Electrophoresis, 35(9), 1308-1314 (2014).

  43. "Applications of capillary electrophoresis in characterizing recombinant protein therapeutics", Shuai Sherry Zhao, and David D. Y. Chen, Electrophoresis, 35(1), 96-108 (2014).

  44. "Live cell refractometry based on non-SPR microparticle sensor", Chang Liu, David D. Y. Chen, Lirong Yu, and Yong Luo, Electrophoresis, 34, 1526-1529 (2013).

  45. "Micro- and macroheterogeneity of N-glycosylation yields size and charge isoforms of human sex hormone binding globulin circulating in serum", Zeynep Sumer-Bayraktar, Terry Nguyen-Khuong, Roxana Jayo, David D. Y. Chen, Sinan Ali, Nicolle H. Packer, and Morten Thaysen-Andersen, Proteomics, 12, 3315-3327 (2012).

  46. "CAPILLARY ELECTROPHORESIS MASS SPECTROMETRY FOR THE CHARACTERIZATION OF O-ACETYLATED N-GLYCANS FROM FISH SERUM", Roxana G. Jayo, Jianjun Li, and David D. Y. Chen, Analytical Chemistry, 84, 8756-8762 (2012).

  47. "Capillary electrophoresis mass spectrometry for analysis of complex samples", Shuai Sherry Zhao, Xuefei Zhong, Cai Tie, and David D. Y. Chen, Proteomics, 12, 2991-3012 (2012).

  48. "Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis–tandem mass spectrometry", Laiel C. Soliman, Yu Hui, Amitha K. Hewavitharana, and David D.Y. Chen, Journal of Chromatography A, 1267, 162-169 (2012).

  49. "A new derivatization method coupled with LC-MS/MS to enable baseline separation and quantification of dimethylarginines in human plasma from patients to receive on-pump CABG surgery", Yu Hui, Michael Wong, Joo-oll Kim, Jennifer Love, David M. Ansley, and David D.Y. Chen, Electrophoresis, 33, 1911-1920 (2012).

  50. "Atmospheric pressure ion lens extends the stable operational region of an electrospray ion source for capillary electrophoresis-mass spectrometry", Shuai Sherry Zhao, Xuefei Zhong and David D. Y. Chen, Electrophoresis, 33, 1322-1330 (2012).

  51. "A simple and robust LC-MS/MS method for quantification of free 3-nitrotyrosine in human plasma from patients receiving on-pump CABG surgery", Yu Hui, Michael Wong, Shuai S. Zhao, Jennifer A. Love, David M. Ansley and David D. Y. Chen, Electrophoresis, 33, 697-704 (2012).

  52. "Development and Application of a LC-MS/MS Method to Quantify Basal Adenosine Concentration in Human Plasma from Patients Undergoing On-Pump CABG Surgery", Yu Hui, Shuai Sherry Zhao, Jennifer A. Love, David M. Ansley and David D. Y. Chen, Journal of Chromatography B, 855-856, 30-36 (2012).

  53. "The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion", Koen Raedschelders, David M. Ansley and David D. Y. Chen, Pharmacology Therapeutics, 133, 230-255 (2012).

  54. "Local delivery of antimicrobial peptides using self-organized TiO2 nanotube arrays for peri-implant infections", Menghan Ma,Mehdi Kazemzadeh-Narbat,Yu Hui, Shanshan Lu, Chuanfan Ding, David D. Y. Chen, Robert E. W. Hancock and Rizhi Wang, Journal of Biomedical Materials Research Part A, 100A, 178-285 (2012).

  55. "Flow-Through Microvial Facilitating Interface of Capillary Isoelectric Focusing and Electrospray Ionization Mass Spectrometry", Xuefei Zhong, E. Jane Maxwell, Chitra Ratnayake, Scott Mack and David D. Y. Chen, Analytical Chemistry, 83, 8748-8755 (2011).

  56. "Potential of Two-Dimensional Electro-Fluid-Dynamic Devices for Continuous Purification of Multiple Components from Complex Samples", Chang Liu, Yong Luo, E. Jane Maxwell, Ning Fang and David D. Y. Chen, Analytical Chemistry, 83, 8208-8214 (2011).

  57. "A promising capillary electrophoresis–electrospray ionization–mass spectrometry method for carbohydrate analysis", E. Jane Maxwell, Chitra Tatnayake, Roxana Jayo, Xuefei Zhong and David D. Y. Chen, Electrophoresis, 32, 2161-2166 (2011).

  58. "Mass Transport in a Micro Flow-Through Vial of a Junction-at-the-Tip Capillary Electrophoresis-Mass Spectrometry Interface", Xuefei Zhong, E. Jane Maxwell and David D. Y. Chen, Analytical Chemistry, 83, 4916-4923 (2011).

  59. "Differences in myocardial PTEN expression and Akt signalling in type 2 diabetic and nondiabetic patients undergoing coronary bypass surgery", Baohua Wang, Koen Raedschelders, Jayant Shravah, Yu Hui, Hajieh G. Safaei, David D. Y. Chen, R. C. Cook, Guy Fradet, C. L. Au, and David M. Ansley, Clinical Endocrinology, 74, 705-713 (2011).

  60. "Analyte Distribution at Channel Intersections of Electro-Fluid-Dynamic Devices", Chang Liu, Yong Luo, Ning Fang and David D. Y. Chen, Analytical Chemistry, 83, 1189-1192 (2011).

  61. "Asymmetrical Emitter Geometries for Increased Range of Stable Electrospray Flow Rates", E. Jane Maxwell, Xuefei Zhong and David D. Y. Chen, Analytical Chemistry, 82, 8377-8381 (2010).

  62. "Free fatty acids composition in adipocere of the Kwäday Dän Ts’ìnch?ancient remains found in a glacier", Chang Liu, Hyun Mee Park, Maria Victoria Monsalve and David D. Y. Chen , Journal of Forensic Sciences, 55, 1039-1043 (2010).

  63. "Decoupling CE and ESI for a More Robust Interface with MS", E. Jane Maxwell, Xuefei Zhong, Hong Zhang, Nikita van Zeijl and David D. Y. Chen, Electrophoresis, 31, 1130-1137 (2010).

  64. "Reverse of Mixing Process with a Two-Dimensional Electro-Fluid-Dynamic Device", Chang Liu, Yong Luo, E. Jane Maxwell, Ning Fang and David D. Y. Chen, Analytical Chemistry, 82, 2182-2185 (2010).

  65. "Propofol protects against hydrogen peroxide-induced injury in cardiac H9c2 cells via Akt activation and Bcl-2 up-regulation", Baohua Wang, Jayant Shravah, Honglin Luo, Koen Raedschelders, David D. Y. Chen and David M. Ansley, Biochemical and Biophysical Research Communications, 389, 105-111 (2009).

  66. "Target-achieved propofol concentration during on-pump cardiac surgery: a pilot dose-finding study", Koen Raedschelders, Yu Hui, Bradley Laferlita, Tao Luo, Hong Zhang, David D. Y. Chen and David M. Ansley, Canadian Journal of Anesthesia, 56, 658-666 (2009).

  67. "Rationale, design and baseline characteristics of the PROJECT II study: PROpofol CardioproTECTion for Type II diabetics A randomized, controlled trial of high-dose propofol versus isoflurane preconditioning in patients undergoing on-pump coronary artery bypass graft surgery", David M. Ansley, Koen Raedschelders, David D. Y. Chen and Peter T. Choi, Contemporary Clinical Trials, 30, 380-385 (2009).

  68. "Quantitative analysis of propofol in whole blood using capillary electrophoresis", Yu Hui, Koen Raedschelders, Hong Zhang, David M. Ansley and David D. Y. Chen, Journal of Chromatography B, 877, 703-709 (2009).

  69. "Field distribution in an electrospray ionization source determined by finite element method", Xuefei Zhong, Rong Yi, Alison E. Holliday and David D.Y. Chen, Rapid Communication in Mass Spectrometry, 23, 689-697 (2009).

  70. "Behavior of Targeting ligands stimulate endocytosis following binding to the alpha-v beta-3 integrin", Sonya Cressman, Ying Sun, Elizabeth J. Maxwell, Ning Fang and David D. Y. Chen, International Journal of Peptide Research & Therapeutics, 15, 49-59 (2009).

  71. "Twenty years of interface development for capillary electrophoresis-electrospray ionization-mass spectrometry", E. Jane Maxwell and David D.Y. Chen, Analytica Chimica Acta, 627, 25-33 (2008).

  72. "Behavior of Interacting Species in Vacancy Affinity Capillary Electrophoresis Described by Mass Balance Equation", Ying Sun, Ning Fang, David D.Y. Chen, Electrophoresis, 29, 3333-3341 (2008).

  73. "Determination of potentially anti-carcinogenic flavonoids in wines by micellar electrokinetic chromatography", Ying Sun, Ning Fang, David D.Y. Chen, Kingsley K. Donkor, Food Chemistry, 106 , 415-420 (2008).

  74. "Capillary Electrophoresis Frontal Analysis for Characterization of Alpha-v Beta-3 Integrin Binding Interactions", Ying Sun, Sonya Cressman, Ning Fang, Pieter R. Cullis, and David D. Y. Chen , Analytical Chemistry, 80, 3105-3111 (2008).

  75. "Propofol reduces apoptosis and up-regulates endothelial nitric oxide synthase protein expression in hydrogen peroxide-stimulated human umbilical vein endothelial cells", Baohua Wang, Tao Luo, David D. Y. Chen and David M. Ansley, Anesthesia and Analgesia, 105, 1027-1033 (2007).

  76. "Systematic optimization of exhaustive electrokinetic injection combined with micellar sweeping in capillary electrophoresis", Ning Fang, Pingjia Meng, Hong Zhang, Ying Sun and David D. Y. Chen , The Analyst 132 , 127-134 (2007).

  77. "Computer simulation of different modes of ACE based on the dynamic complexation model", Ning Fang, Ying Sun, Jingyan Zheng and David D. Y. Chen , Electrophoresis 28 , 3214-3222 (2007).

  78. "Analysis of amphetamine, methamphetamine and methylenedioxy-methamphetamine by micellar capillary electrophoresis using cation-selective exhaustive injection", Pinjia Meng, Ning Fang, Meng Wang, Huwei Liu, David D.Y. Chen , Electrophoresis 27 , 3210-3217 (2006).

  79. "Electrospray ionization source geometry for mass spectrometry: past, present, and future ", Irina Manisali, David D.Y. Chen, and Bradley B. Schneider , TrAC Trends in Analytical Chemistry 27 , 3210-3217 (2006).

  80. "Behavior of Interacting Species in Capillary Electrophoresis Described by Mass Transfer Equation", Ning Fang and David D. Y. Chen , Analytical Chemistry 78 , 1832-1840 (2006).

  81. "An Enumeration Algorithm for Determination of Binding Constants in Capillary Electrophoresis", Ning Fang and David D. Y. Chen , Analytical Chemistry, 77, 2415-2420 (2005).

  82. "A General Approach to High Efficiency Simulation of Affinity Capillary Electrophoresis", Ning Fang and David D. Y. Chen , Analytical Chemistry 77 , 840-847 (2005).

  83. "Continuous Electrophoretic Purification of Individual Analytes from Multicomponent Mixtures", David McLaren and David D. Y. Chen , Analytical Chemistry 76, 2298-2305(2004).

  84. "Determination of Shapes and Maximums of Analyte Peaks Based on Solute Mobilities in Capillary Electrophoresis", Ning Fang, Eon Ting, and David D. Y. Chen , Analytical Chemistry 76 , 1708-1714 (2004).

  85. "Complementary on-line preconcentration strategies for steroids by capillary electrophoresis", Britz-McKibbin P, Ichihashi T, Tsubota K, Chen DDY, Terabe S , JOURNAL OF CHROMATOGRAPHY A 1013 , 65-76 (2003).

  86. "Optimization of Cellular Nucleotide Extraction and Sample Preparation for Nucleotide Pool Analyses using Capillary Electrophoresis", Miriam K. Grob, Kylie O'Brien, Jian Hua Chu, David D.Y. Chen , Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 788 , 103-111 (2003).

  87. "A Quantitative Study of Continuous Flow Counterbalanced Capillary Electrophoresis for Sample Purification", David G. McLaren and David D. Y. Chen , Electrophoresis 24 , 2887-2895 (2003).

  88. "Velocity-Difference Induced Focusing of Xanthine and Purine Metabolites by capillary electrophoresis Using a Dynamic pH Juction", P. Britz-McKibbin and D. D. Y. Chen , Chromatographia 57 , 87-93 (2003).

  89. "Molecular interaction in capillary electrophoresis", Chiara Galbusera and David DY Chen , Current Opinion in Biotechnology 14 , 126-130 (2003).

  90. "Multiple Sprayer System for High-Throughput Electrospray Ionization Mass Spectrometry", Bradley B. Schneider, D. J. Douglas and David D. Y. Chen , Rapid Communications in Mass Spectrometry 16 , 1982-1990 (2002).

  91. "An Atmospheric Pressure Ion Lens that Improves Nebulizer Assisted Electrospray Ion Source", Bradley B. Schneider , Journal of the American Society for Mass Spectrometry 13 , 906-913 (2002).

  92. "Affinity capillary electrophoresis using low concentration additive with the consideration of relative mobilities", Chiara Galbusera, Mark Thachuk, Ersilia De Lorenzi and David D. Y. Chen , Anal. Chem. 74 , 1903-1914 (2002).

  93. "Proton and Hydroxide Ion Mobility in Capillary Electrophoresis", Angela B. Duso and David D. Y. Chen , Analytical Chemistry 74 , 2938-2942 (2002).

  94. "Applications of On-Line Weak Affinity Interactions in Free Solution Capillary Electrophoresis", Niels H. H. Heegaard, Mogens H. Nissen and David D. Y. Chen , Electrophoresis 23(6) , 815-822 (2002).

  95. "Univalent salts as modifiers in micellar capillary electrophoresis", David G. McLaren, Olivier Boulat, and David D. Y. Chen , Electrophoresis 23(12) , 1912-1920 (2002).
  96. "Accurately Describing Weak Analyte-Additive Interactions by Capillary Electrophoresis", Philip Britz-McKibbin and David D. Y. Chen , Electrophoresis 23(6) , 880-888 (2002).
  97. "An Ion Lens to Improve Electrospray Ionization at Low Solution Flow-Rates", Bradley B. Schneider, D. J. Douglas, and David D.Y. Chen , Rapid Communications in Mass Spectrometry 15 , 2168-2175 (2001).
  98. "Competence Development by Haemophilus influenzae is Regulated by Availability of Nucleic Acid Precursors", L. P. Macfadyen, D. Chen, H. C. Vo, D. Liao, R. Sinotte AND R. J. Redfield , Molecular Microbiology 40 , 700-707 (2001).
  99. "Analysis of free amino acids in human plasma by capillary electrophoresis with laser induced fluorescence: Potential for emergency diagnosis of inborn errors of metabolism", O. Boulat, D. G. McLaren, E. A. Arriaga, D. D.Y. Chen , J. Chromotogra. B 754 , 217-228 (2001).

  100. "Determination of Collision-Induced Dissociation Rates of Bradykinin in the Interface Region of an ESI-MS", B.B. Schneider, D.J. Douglas, and D.D.Y. Chen , Journal of the American Society for Mass Spectrometry 12(7) , 772-779 (2001).
  101. "Ion Fragmentation in an Electrospray Ionization-Mass Spectrometer Interface with Different Gases", B.B. Schneider, D.J. Douglas, and D.D.Y. Chen , Rapid Communications in Mass Spectrometry 15 , 249-257 (2001).

  102. "Velocity-Difference Induced Focusing of Nucleotides in Capillary Electrophoresis with a Dynamic pH Junction", P. Britz-Mckibbin, G. M. Bebault, and D. D. Y. Chen , Anal. Chem. 72 , 1729-1735 (2000).
  103. "Selective focusing of Catecholamines and Weakly Acidic Compounds in Capillary Electrophoresis Using a Dynamic pH Junction", P. Britz-Mckibbin and D.D.Y. Chen , Anal. Chem. 72 , 1242-1252 (2000).
  104. "Collision Induced Dissociation of Ions within the Orifice-Skimmer Region of an Electrospray Mass Spectrometer", B. B. Schneider and D.D.Y. Chen , Anal. Chem. 72 , 791-799 (2000).
  105. "Analysis of g-Carboxyglutamic Acid Content of Protein, Urine and Plasma by Capillary Electrophoresis and Laser Induced Fluorescence", P. Britz-Mckibbin, H.C. Vo, R.T.A. MacGillivray, and D.D.Y. Chen , Anal. Chem. 71 , 1633-1637 (1999).
  106. "Monte Carlo Simulation of Error Propagation in the Determination of Binding Constants from Rectangular Hyperbolae. 2. Effect of the Maximum Response Range", M.T. Bowser and D. D.Y. Chen , J. Phys. Chem. A 103 , 197-202 (1999).
  107. "Undercarboxylation of recombinant prothrombin revealed by analysis of g-carboxyglutamic acid by capillary electrophoresis and laser induced fluorescence", H.C. Vo, P. Britz-Mckibbin, D.D.Y. Chen, and R.T.A. MacGillivray , FEBS Letters 445 , 256-260 (1999).

  108. "Analysis of Epinephrine from Fifteen Different Dental Anesthetic Formulations by Capillary Electrophoresis", P. Britz-Mckibbin, J. Wong, and D.D.Y. Chen , J. Chromatogr. A 853 , 535-540 (1999).
  109. "Monte Carlo Simulations of Error Propagation in the Determination of Binding Constants from Rectangular Hyperbolae. 1. Ligand Concentration Range and Binding Constant", M.T. Bowser and D.D.Y. Chen , J. Phy. Chem. A 102 , 8063-8071 (1998).
  110. "Higher Order Equilibria and Their Effects on Analyte Migration Behavior in Dynamic Complexation Capillary Electrophoresis", M.T. Bowser and D.D.Y. Chen , Anal. Chem. 70 , 3261-3270 (1998).
  111. "A Water Soluble Tetraethylsulfonate Derivative of 2-Methyl Resorcinarene as a Novel Additive for Capillary Electrophoresis", P. Britz-Mckibbin and D.D.Y. Chen , Anal. Chem 70 , 907-912 (1998).

  112. "The properties of Multivariate Binding Isotherms in Capillary Electrophoresis", M.T. Bowser, A.R. Kranack, and D.D.Y. Chen , Anal. Chem 70 , 1076-1084 (1998).

  113. "Dynamic Complexation of Solutes in Capillary Electrophoresis", M.T. Bowser and D.D.Y. Chen, invited review , Electrophoresis 19 , 383-387 (1998).

  114. "The effects of a Mixture of Charged and Neutral Additives on Analyte Migration Behavior in Capillary Electrophoresis", A.R. Kranack, M.T. Bowser, P. Britz-Mckibbin, and D.D.Y. Chen , Electrophoresis 19 , 338-396 (1998).

  115. "Quantitative Assay for Epinephrine from Dental Anethetic Solutions by Capillary Electrophoresis", P. Britz-Mckibbin and D.D.Y. Chen, invited paper , The Analyst 123 , 1461-1463 (1998).

  116. "Analyte-Additive Interactions in Nonaqueous Capillary Electrophoresis: A Critical Review", M.T. Bowser, A.R. Kranack, and D.D.Y. Chen, invited review , TrAC Trends in Analytical Chemistry 17 , 424-434 (1998).

  117. "The Effect of Complexation Additives on Analyte Migration Behavior in Capillary Electrochromatography", Michael T. Bowser and David D. Y. Chen , Electrophoresis 19 , 1452-1460 (1998).

  118. "Recent Developments towards a Unified theory for Separation Science", M.T. Bowser and D.D.Y. Chen, invited review , Electrophoresis 19 , 1586-1589 (1998).

  119. "Extra-Separation Peak Broadening in Capillary Electrophoresis", C. A. Lucy, K.K.-C. Yeung, X. Peng, and D.D.Y. Chen , LC-GC 16(1) , 26-31 (1998).

  120. "The Variance Contributed By Pressure Injection in Capillary Electrophoresis", X. Peng and D.D.Y. Chen , J. Chromatogr. 767 , 205-216 (1997).

  121. "Quantitative Description of Migration Behavior of Porphyrins Based on the Dynamic Complexation Model in a Nonaqueous Capillary Electrophoresis System", M.T. Bowser, E.D. Sternberg and D.D.Y. Chen , Electrophoresis 18 , 82-91 (1997).

  122. "Quantitative Description of Analyte Migration Behavior Based on the Dynamic Complexation Model in Capillary Electrophoresis", X. Peng, G.M. Bebault, S.L. Sacks and D.D.Y. Chen , Canadian Journal of Chemistry 75 , 507-517 (1997).

  123. "Quantitative Description of Analyte Migration Behavior Based on Dynamic Complexation in Capillary Electrophoresis with One or More Additives", X. Peng, M.T. Bowser, P. Britz-McKibbin, G.M. Bebault, J. Morris, and D.D.Y. Chen , Electrophoresis 18 , 706-716 (1997).

  124. "The Prediction of the Migration Behavior of Analytes in Capillary Electrophoresis Based on Three Fundamental Parameters", P. Britz-Mckibbin and D.D.Y. Chen , J. Chromatogr. 781 , 23-34 (1997).

  125. "Redefining the Separation Factor: a potential pathway to a unified separation Science", M.T. Bowser and D.D.Y. Chen , Electrophoresis 18 , 2928-2934 (1997).

  126. "Development and Application of a Nonaqueous Capillary Electrophoresis System for the Analysis of Porphyrins and Their Oligomers (Photofrin)", M.T. Bowser, E.D.Sternberg and D.D.Y. Chen , Anal. Biochem. 241 , 143-150 (1996).
  127. "Single-Molecule Detection in Capillary Electrophoresis: Molecular Shot Noise as a Fundamental Limit to Chemical Analysis", D.Y. Chen and N.J. Dovichi , Anal. Chem. 68 , 690-696 (1996).

  128. "Single Molecule Detection in Analytical Chemistry", N.J. Dovichi and D.Y. Chen in Optical Probing of Single Molecules, edited by Bache, Moerner, Orrit and Wild, (Verlagsgellschaft, , 1996) , Chapter 3, p233-243.

  129. "Yoctomole Detection Limit by Laser Induced Fluorescence in Capillary Electrophoresis", D.Y. Chen and N.J. Dovichi , J. Chromatogr. B 657 , 265-269 (1994).

  130. "A Simple Laser Induced Fluorescence Detector for Sulforhodamine 101 in a Capillary Electrophoresis System: Detection Limits of 10 Yoctomoles or Six Molecules", D.Y. Chen, Karin Adelhelm, X.L. Cheng and N.J. Dovichi , Analyst 119 , 349-352 (1994).

  131. "Use of 6%T Noncrosslinked Polyacrylamide for DNA Sequencing in Capillary Electrophoresis - Separation of Fragments up to 570 Bases in Length", N. Best, E.Arriaga, D.Y. Chen, and N.J. Dovichi , Anal. Chem. 66(22) , 4063-4067 (1994).

  132. "High Speed and High Accuracy DNA Sequencing by Capillary Gel Electrophoresis in a Simple, Low Cost Instrument: Two color Peak Height Encoded Sequencing at 40� C", H. Lu, E. Arriaga, D.Y. Chen, H. Starke, and N.J. Dovichi , Journal of Chromatography 680(2) , 497-501 (1994).

  133. "The Activation Energy of Single Stranded DNA Moving Through Cross Linked Polyacrylamide Gels at 300 V/Cm: The Effect of Temperature on Sequencing Rate in High Field Capillary Gel Electrophoresis", H. Lu, E. Arriaga, D.Y. Chen, D. Figeys and N.J. Dovichi , Journal of Chromatography 680(2) , 503-510 (1994).

  134. "The Sheath Flow Cuvette in DNA Sequencing by Capillary Gel Electrophoresis and Two Spectral Channel Laser-Induced Fluorescence Detection", J.Z. Zhang, D.Y. Chen, H.R. Harke, and N.J. Dovichi in Capillary Electrophoresis, edited by Norbeto Guzman, (Marcel Dekker, Inc., New York, 1993) , p 631-641.

  135. "High Efficiency Filter Fluorometer for Capillary Electrophoresis: Zeptomole Detection Limits for Fluorescein Thiocarbamyl Amino Acids", E. Arriaga, D.Y. Chen, X.L. Cheng and N.J. Dovichi , J. Chromatogr. A 652 , 347-353 (1993).

  136. "Two-Label Peak-Height Encoded DNA sequencing By Capillary Gel Electrophoresis", D.Y. Chen, H.R. Harke and N.J. Dovichi , Nucleic Acids Research 20(18) , 4873-4880 (1992).

  137. "Formamide modified polyacrylamide gels for DNA sequencing by capillary gel electrophoresis", M-J Rocheleau, R. Grey, D.Y. Chen, H.R. Harke, and N.J. Dovichi , Electrophoresis 13 , 484-486 (1992).

  138. "Low Cost Laser-Induced Fluorescence Detection for Micellar Capillary Zone Electrophoresis: Zeptomole Detection of Tetramethyl Rhodamine Thiocarbamyl Amino Acid Derivatives", J.Y. Zhao, D.Y. Chen, and N.J. Dovichi , J. Chromatogr. 608 , 117-120 (1992).

  139. "Attomole and Sub-attomole Detection of Thiohydantoin Derivatives of Amino Acids by Capillary Zone Electrophoresis Separation and Laser-based Detection", J.Y. Zhao, K.C. Waldron, D.Y. Chen and N.J. Dovichi in Frontiers and New Horizons in Amino acid Research, edited by Katsuji Takai, (Elsevier Science Publishers, , 1992) , p 239-248.

  140. "Low-cost, high-sensitivity laser-induced fluorescence detection for DNA sequencing by capillary gel electrophoresis", D.Y. Chen, H.P. Swerdlow, H.R. Harke, J.Z. Zhang, and N.J. Dovichi , J. Chromatogr. 559 , 237-246 (1991).

  141. "Single-color laser-induced fluorescence detection and capillary gel electrophoresis for DNA sequencing", D.Y. Chen, H.P. Swerdlow, H.R. Harke, J.Z. Zhang, and N.J. Dovichi , SPIE: Optical methods for Ultrasensitive Detection and Analysis: Techniques and Applications 1435 , 161-167 (1991).

  142. "Three DNA sequencing methods based on capillary gel electrophoresis and laser-induced fluorescence", H.P. Swerdlow, J.Z. Zhang, D.Y. Chen, H.R. Harke, R. Grey, S. Wu, C. Fuller, and N.J. Dovichi , Anal. Chem. 63 , 2835-2841 (1991).

  143. "High sensitivity laser-induced fluorescence detection for capillary electrophoresis", J.Z. Zhang, D.Y. Chen, H.R. Harke, S. Wu, and N.J. Dovichi , Clinical Chem. 37 , 1492-1496 (1991).

  144. "DNA Sequencing by Capillary Gel Electrophoresis and Laser-Induced Fluorescence Detection", J.Z. Zhang, D.Y. Chen, H.R. Harke and N.J. Dovichi , Analytical Sciences 7 , 1485-1489 (1991).

  145. "Interaction of Capillary Zone Electrophoresis with a Sheath Flow Cuvette Detector", Y.F. Cheng, S. Wu, D.Y. Chen, and N.J. Dovichi , Anal. Chem. 62 , 496-503 (1990).


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Last modified Dec, 2022.